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Fifty percent inhibition concentrations (IC50) and relative resistance of curcumin and cantharidin in sensitive and multidrug-resistant CEM leukemia tumor cell lines [16]
| Curcumin | Cantharidin | |
| Growth inhibition assay: | ||
| CCRF-CEM | 30 μM | 20 μM |
| CEM/ADR5000 | 28 μM | 17 μM |
| Relative resistance | 0.9 | 0.9 |
| MTT-Assay: | ||
| CCRF-CEM | >13.5 μM | 1.9 μM |
| CEM/VBL100 | >13.5 μM | 1.4 μM |
| Relative resistance: | n.d. | 1.4 |
| CEM/E1000 | 13.5 μM | 0.76 μM |
| Relative resistance | n.d. | 0.4 |
n.d.: not determined
