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Metabolism of homocysteine and the remethylationto methionine by the alternative folate and betaine pathways. THF: tetrahydrofolate; MTHFR: methylentetrahydrofolate reductase; BHMT: betaine-homocysteine methyltransferase; MTR: methionine synthase reductase. Note: in boxes – choline, betaine, folate and methionine concentrations in plasma
