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. 2007 Aug;171(2):608–616. doi: 10.2353/ajpath.2007.070068

Figure 1.

Figure 1

Hearing function deficit in Tmprss1−/− mice. Adult wild-type, Tmprss1 heterozygous, and Tmprss1 knockout mice were subjected to click-evoked ABR measurements. The amplitude of the response (four peaks labeled from I to IV) is measured in millivolts. The latency is shown in milliseconds. Click stimulus intensity is indicated in decibel attenuation. Maximum stimulus intensity corresponds to 0 dBA. The green portion of the graph highlights the waveform chosen to determine threshold. A: Representative ABR response of wild-type mice at 0, 20, and 40 dBA. Arrow indicates ABR threshold. B: Representative ABR response of Tmprss1−/− mice at 0, 5, 10, 15, and 20 dBA. Arrow indicates ABR threshold. C: Quantification of the average ABR thresholds of wild-type, Tmprss1 heterozygote, and Tmprss1-null mice. Graph indicates mean ± SEM.