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. Author manuscript; available in PMC: 2008 Jan 15.
Published in final edited form as: J Infect Dis. 2007 Jun 5;196(2):321–327. doi: 10.1086/518795

Figure 2.

Figure 2

Signaling activities by human umbilical vein endothelial cells (HUVECs) as a ratio of intercellular adhesion molecule (ICAM)-1 cross-linking caused by different parasite lines (C24, ItG, and A4) and red blood cells (RBCs) in the absence and presence of blocking monoclonal antibody (MAb) 15.2 and with MAb15.2 on its own (15.2). The response of HUVECs homozygous for the ICAM-1Kilifi allele (Kilifi) with reduced ICAM-1 adhesion is also shown. The protocols for determining the phosphorylation of specific kinases is described in Materials and Methods and is plotted as the ratio of ICAM-1 cross-linking. Mock-incubated uninfected RBCs were used as a control. P values for specific comparisons are indicated on each graph.