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. 2007 Aug 1;117(8):2133–2144. doi: 10.1172/JCI31807

Figure 10. Defective post-progenitor erythroblast response to phenylhydrazine in Foxo3–/– mice.

Figure 10

WT and Foxo3-deficient mice were treated with phenylhydrazine (100 mg/kg) or PBS and sacrificed 24 hours later. (A) Flow cytometry analysis of relative frequency of mature erythroblasts in the bone marrow, spleen, and blood, calculated by the ratio of mature erythroblasts (CD71–TER119+) to total erythroblasts (CD71+TER119+ and CD71–TER119+). n = 3 in each group; *P < 0.05, Student’s t test. (B) Measurement of ROS concentration in erythroblasts (TER119+ cells). #P < 0.01; **P < 0.001.