Figure 1.

The T4 genomic macroarray. Although the terminally redundant, 172 kb T4 chromosome is linear, the ends are is circularly permutated, and there are no fixed telomeres. This results in a circular genetic map as depicted here. The location and position of PCR fragments included in the genomic array are indicated with yellow tabs with identifying numbers that correspond to the PCR loci (LP numbers) listed in Table 1. Putative T4 origins of DNA replication have been placed on the map as reported previously 8, 21 and are indicated with green lollipops and identifiers (a, b, ect.). Major open reading frames (>100 amino acids) are indicated with arrows. These were placed on the genetic map using pDRAW32 and were color coded to indicate the timing of transcription, green, early; yellow, middle; and red, late transcripts based on Luke et al 44. Additionally, the position of two smaller T4 late genes soc and rI.-1 are indicated with red arrows near oriA and oriC, respectively.