Table 2.
Functional classification of S. coelicolor M145 genes missing or divergent in S. lividans TK21
| Function a | Total Present b | Number Missing/Divergent | Percent Missing/Divergent |
| Cell processes | 800 | 32 | 4 % |
| Macromolecule metabolism | 496 | 20 | 4 % |
| Amino acids biosynthesis | 123 | 3 | 2 % |
| Nucleotide biosynthesis | 30 | 0 | 0 % |
| Ribosomal constituents | 67 | 0 | 0 % |
| Biosynthesis of cofactors and carriers | 118 | 0 | 0 % |
| Central intermediary metabolisms | 111 | 4 | 4 % |
| Degradation of small molecules | 200 | 6 | 3 % |
| Energy metabolism | 189 | 1 | 1 % |
| Fatty acid and phosphatidic acid biosynthesis | 56 | 4 | 7 % |
| Secondary metabolism | 277 | 3 | 1 % |
| Periplasmic, exported or lipoproteins | 1318 | 84 | 6 % |
| Two-component systems | 165 | 7 | 4 % |
| RNA polymerase core enzyme binding | 88 | 3 | 3 % |
| Regulatory proteins | 673 | 39 | 6 % |
| Protein kinases | 39 | 1 | 3 % |
| Laterally acquired elements | 139 | 95 | 68 % |
| Not classified | 565 | 30 | 5 % |
| Hypothetical proteins | 2371 | 293 | 12 % |
| Total | 7825 | 625 | 8% |
a protein classification scheme derived from EcoCyc database; downloaded from http://www.sanger.ac.uk/Projects/S_coelicolor/scheme.shtml
b Total number of proteins present in S. coelicolor chromosome in each category