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. Author manuscript; available in PMC: 2008 May 18.
Published in final edited form as: Cancer Lett. 2006 Nov 3;250(1):36–46. doi: 10.1016/j.canlet.2006.09.013

Figure 4. Altered AQP expression in HCC is not unique to the H4IIE HCC model.

Figure 4

(a). Representative immunohistochemical images of normal mouse liver tissue probed with an antibody specific against AQP 9 (x100 magnification). Approximate representative hepatic lobule zones are labeled Z1, Z2 and Z3 (left panel). Increased magnification (x400) of zones 1 and 3 demonstrate increased Z3 (right panel) staining versus Z1 (center panel). (b) Representative immunohistochemical images of HCC tissue and surrounding normal liver tissue from a mouse-DEN model of HCC probed with anti-AQP 9 antibody (x20 and x400 magnification).