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. 2007 Jun 18;35(13):4474–4484. doi: 10.1093/nar/gkm463

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Published by Oxford University Press (2007)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Binding of furamidine to a 495 response units surface of a stem-loop duplex oligonucleotide (A) and 504 response units surface of a single-stranded oligonucleotide (B). The equilibrium level of binding was determined for each furamidine concentration for the duplex oligonucleotide (C) or the single-stranded oligonucleotides (D). The graphs represent a fit using a two binding-site model for the stem-loop duplex oligonucleotide (C) or a single binding-site model for the single-stranded oligonucleotide (D). Twofold increments of furamidine concentration (0.097, 0.19, 0.39, 0.78, 1.56, 3.125, 6.25, 12.5 and 25 µM) were used.