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. 2003 Aug 12;100(18):10364–10369. doi: 10.1073/pnas.1333957100

Table 2. Nonsynonymous SNPs.

SNP Amino acid Charge Domain Conservation Reference allele Substitute allele
10 (C/T) R4C +/polar Signal Low Divergent Moderate
148 (G/A) D50N −/polar Extracellular Low Conserved Moderate
452 (A/C) N151T Polar/polar Extracellular Moderate Conserved Conserved
714 (C/G) N238K Polar/+ Extracellular Moderate Conserved Divergent
1040 (C/A) A347E Nonpolar/− Extracellular Low Conserved Divergent
1142 (A/G) K381R +/+ Extracellular High Divergent Divergent
1948 (G/A) V6501 Nonpolar/nonpolar Transmembrane Moderate Conserved Conserved
2021 (C/T) T6741 Nonpolar/polar Transmembrane/cytoplasmic Moderate Conserved Conserved