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siRNA analyses. Transfection of Ian4-specific siRNA increased T cell apoptosis. Bars depict the percentage of cells with subdiploid DNA after 48 h of treatment. *, Statistically similar to each other and P < 0.025 vs. each of the other four groups. The number of independent measurements is shown in parentheses. Two other Ian4 siRNAs were less effective (data not shown).
