Table 1. In vivo role of Ag presentation in ovx-induced T cell expansion.

	T cells in S phase, % of T cells	T cells in sub-G0/G1 phase, % of T cells	TNF-producing T cells, % of BM white cells
DO 11.10 sham	2.23 ± 0.4	0.56 ± 0.2	0.43 ± 0.1
DO 11.10 ovx	1.87 ± 0.7	0.78 ± 0.4	0.32 ± 0.1
DO 11.10 sham + ovalbumin	4.4 ± 0.5*	1.6 ± 0.2*	0.67 ± 0.2
DO 11.10 ovx + ovalbumin	14.1 ± 2.6*†	0.7 ± 0.1†	1.8 ± 0.4*†

Ovx fails to increase T cell proliferation (cells in S phase), to decrease T cell apoptosis (cells in sub-G₁₀/G₁ phase), and to increase BM T cells in DO 11.10 mice (mean ± SEM).

^*P < 0.05 as compared to untreated shams.

^†P < 0.05 as compared to ovalbumin-treated shams.