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. 2003 Aug 19;100(18):10440–10445. doi: 10.1073/pnas.1832855100

Fig. 2.

Fig. 2.

Commitment of primitive cells with cardiac hypertrophy. (A and B; the same field) A cardiac progenitor (A, arrowhead) shows c-kit on the surface membrane (green) and GATA-4 (A, red) in the nucleus, and the myocyte progenitor (B, arrow) exhibits in its nucleus GATA-4 (A, red) and MEF2 (B, white). (C and D; the same field) A cardiac progenitor (C, arrowhead) shows MDR1 on the surface membrane (purple) and GATA-4 (C, red) in the nucleus, and a myocyte progenitor (D, arrow) exhibits in its nucleus GATA-4 (C, red) and MEF2 (D, white). (E, F, and G) Myocyte precursors (arrows) show on the surface membrane c-kit (E, green), MDR1 (F, purple), or Sca-1-like (G, yellow). A thin cytoplasmic layer is positive for cardiac myosin (E-G, red) and nuclei express MEF2 (E-G, white). (Bars = 10 μm.)