Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2007 Jul 31;104(32):13040–13045. doi: 10.1073/pnas.0703213104

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2007 by The National Academy of Sciences of the USA

Freely available online through the PNAS open access option.

PMC Copyright notice

Fig. 5. — Increased propensity of skin carcinogenesis in Hipk2^+/− and Hipk2^−/− mutant mice. (A) Two-stage skin carcinogenesis paradigm induces more tumors in Hipk2^+/− and Hipk2^−/− mutants compared with WT littermates (P < 0.0001). (B) Incubation time for tumor formation is much shorter in Hipk2^+/− and Hipk2^−/− mutants (P = 0.0151 for WT and Hipk2^+/−; P = 0.004 for WT and Hipk2^−/−). (C) A higher percentage of the skin tumors in Hipk2^+/− and Hipk2^−/− mutants develop into carcinoma (P < 0.0001). Data in B and C are presented by using the Kaplan–Meier method, and statistical analyses are performed by using Student's t test.