Table 1.
In vitro growth of primary SIVsm isolates belonging to different lineages on human cell lines
| MT2 | SupT1 | CEMx174 | CEMss | PM1 | Molt4 Clone8 | ||
|---|---|---|---|---|---|---|---|
| Lineage 1 | M919 | +++2(w53) | +++(w3) | ++(w8) | - | - | - |
| M935 | +++(w5) | +++(w6) | +++(w8) | - | +(w4) | - | |
| M923 | ++(w6) | - | +(w4) | - | - | - | |
| Lineage 2 | M926 | NT | NT | +++(w6) | NT | ±(w4) | - |
| M946 | +++(w4) | +++(w6) | +++(w3) | - | - | - | |
| Lineage 3 | M949 | - | - | +++(w5) | - | - | - |
| M951 | - | ±(w6) | +++(w6) | - | - | - | |
| Lineage 4 | M932 | +++(w6) | - | +++(w5) | - | - | - |
| Lineage 6 | D215 | - | +++(w7) | +++(w6) | - | +(w5) | - |
1
Uninfected SM PBMC co-cultivated with PBMC from SIVsm naturally-infected SM;
2
defined based on P27 antigen concentration at the peak of viral replication (noted in the parenthesis); ±30-100 pg;+100-500pg;++501-2000pg;+++>2000pg per well;
3
w =week post cell inoculation