Table 1.
Protocol-assigned and actual doses used during Study 107
Deferasirox, mg/kg/day | ||||
Protocol assigned dose | 5 | 10 | 20 | 30 |
Actual mean dose ± SD | 6.2 ± 1.6 | 10.2 ± 1.2 | 19.4 ± 1.7 | 28.2 ± 3.5 |
DFO, mg/kg/day | ||||
Protocol assigned dose | <25 | 25–<35 | 35–<50 | ≥50 |
Actual mean dose ± SD | 33.9 ± 9.9 | 36.7 ± 9.2 | 42.4 ± 6.6 | 51.6 ± 5.8 |
Ratio of actual deferasirox: DFO doses | 1:5.5 | 1:3.6 | 1:2.2 | 1:1.8 |
Abbreviations: DFO, deferoxamine; SD, standard deviation.