Table 2.
Genant-modified Sharp Score: median change from baseline at 12 months in the AIM trial
| Median change from baseline (25th, 75th percentile) | |||
|---|---|---|---|
| Abatacept–MTX (n=424) | Placebo–MTX (n=214) | p (abatacept vs placebo) | |
| Erosion score | 0.00 (0.00, 1.02) | 0.27 (0.00, 1.27) | 0.029 |
| Joint space narrowing | 0.00 (0.00, 0.49) | 0.00 (0.00, 0.97) | 0.009 |
| Total score | 0.25 (0.00, 1.78) | 0.53 (0.00, 2.54) | 0.012 |
Abbreviations: AIM, Abatacept in patients with an inadequate response to methotrexate; MTX, methotrexate.