Table 3.
The IPSS scoring system for MDS
| Prognostic variable | Score value | ||||
|---|---|---|---|---|---|
| 0 | 0.5 | 1.0 | 1.5 | 2.0 | |
| BM blasts % | <5 | 5–10 | – | 11–20 | 21–30 |
| Karyotypea | Good | Intermediate | Poor | ||
| Cytopeniasb | 0 or 1 | 2 or 3 | |||
Note: Scores for risk groups are as follows: Low: 0, Intermediate-1: 0.5–1.0, Intermediate-2: 1.5–2.0, High >2.5.
a
Karytotype: Good: normal, -Y, del(5q), del(20q); Poor: complex (>3 abnormalities), or chromosome 7 anomalies; Intermediate: other abnormalities;
b
Cytopenias: defined as Hb<10g/dl, Absolute neutrophil count <1.5×109/L and platelet count <100×109/L.
Abbreviations: BM, bone marrow; INT, intermediate; IPSS, International Prognostic Scoring System; MDS, myelodysplastic syndromes.