Table 2.

Mean multiple-dose pharmacokinetics of linezolid, administered twice daily, as recommended (modified from Stevens et al 2004)

Parameter	600 mg oral tablet	600 mg IV
Cmax (mcg/mL)	21.2 ± 5.78	15.10 ± 2.52
Cmin(mvg/mL)	6.15 ± 2.94	3.68 ± 2.36
Tmax(hours)	1.03 ± 0.62	0.51 ± 0.03
AUC (mcgh/mL)	138.0 ± 42.1	89.7 ± 31.0
Half-life (hours)	5.40 ± 2.06	4.80 ± 1.70
Clearance (mL/min)	80.0 ± 29.0	123.0 ± 40.0

Abbreviations: AUC, area under the curve.