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Amino acid sequence of the ankyrin repeat regions of DBA/2 (wild-type) p16INK4a. Amino acid substitutions are indicated above or below the site of the polymorphic variants (ankyrin repeats 1 and 2) and tumor-specific mutations (ankyrin repeat 3). The amino acid sequences between BALB/c and DBA/2 were identical in the third and fourth ankyrin repeats.
