Table 4.
Protein domain enrichment found in recently duplicated mouse genes*
| InterPro entry ID | Protein domain description | Number found in 608 duplicated genes | Number found in all 16,515 annotated genes in genome | Enrichment† |
| IPR000276 | Rhodopsin-like GPCR superfamily | 135 | 1229 | 3.0 |
| IPR000725 | Olfactory receptor | 103 | 861 | 3.3 |
| IPR003006 | Immunoglobulin/major histocompatibility complex | 46 | 372 | 3.4 |
| IPR004072 | Vomeronasal receptor, type 1 | 31 | 108 | 7.8 |
| IPR001909 | KRAB box | 23 | 103 | 6.1 |
| IPR001254 | Serine protease, trypsin family | 21 | 117 | 4.9 |
| IPR002401 | E-class P450, group I | 20 | 61 | 8.9 |
| IPR001128 | Cytochrome P450 | 20 | 68 | 8.0 |
| IPR007086 | Zn-finger, C2H2 subtype | 20 | 139 | 3.9 |
| IPR001314 | Chymotrypsin serine protease, family S1 | 19 | 108 | 4.8 |
| IPR002403 | E-class P450, group IV | 17 | 56 | 8.2 |
| IPR002397 | B-class P450 | 13 | 29 | 11.9 |
| IPR001304 | C-type lectin | 13 | 96 | 3.7 |
| IPR000215 | Serpin | 12 | 48 | 6.8 |
| IPR002402 | E-class P450, group II | 9 | 14 | 18.5 |
| IPR006046 | Glycoside hydrolase family 13 | 7 | 8 | 23.0 |
| IPR006047 | Alpha amylase, catalytic domain | 7 | 10 | 19.2 |
| IPR001400 | Somatotropin hormone | 7 | 32 | 6.1 |
| IPR006048 | Alpha amylase, C-terminal all-beta domain | 6 | 7 | 24.7 |
| IPR002018 | Carboxylesterase, type B | 6 | 13 | 12.3 |
| IPR004073 | Vomeronasal receptor, type 2 | 6 | 13 | 12.3 |
| IPR001039 | Major histocompatibility complex protein, class I | 6 | 17 | 9.9 |
| IPR001828 | Extracellular ligand-binding receptor | 6 | 29 | 5.5 |
| IPR002213 | UDP-glucoronosyl/UDP-glucosyl transferase | 5 | 12 | 11.8 |
| IPR002448 | Odour-binding protein | 4 | 9 | 13.2 |
| IPR000068 | Extracellular calcium-sensing receptor | 4 | 10 | 11.0 |
*Only Ensembl gene annotation (608 genes) was used in this analysis. †All results shown are statistically significant with p-values < 10-5 (chi2 test).