Table 5.
Genes that have undergone recent duplication in both the mouse and human genome*
| Refseq† | Gene description |
| NM_007534 | B-cell leukemia/lymphoma 2 related protein A1b (Bcl2a1b) |
| NM_007558 | Bone morphogenetic protein 8a (Bmp8a) |
| NM_007812 | Cytochrome P450, 2a5 (Cyp2a5) |
| NM_008181 | Glutathione S-transferase, alpha 1 (Ya) (Gsta1) |
| NM_010390 | Histocompatibility 2, Q region locus 1 (H2Q1) |
| NM_009467 | UDP-glucuronosyltransferase 2 family, member 5 (Ugt2b5) |
| NM_009669 | Amylase 2, pancreatic (Amy2) |
| NM_009888 | Complement component factor h (Cfh) |
| NM_010856 | Myosin heavy chain, cardiac muscle, adult (Myhca) |
| NM_013778 | Aldo-keto reductase family 1, member C13 (Akr1c13) |
| NM_022033 | 3-Oxoacid CoA transferase 2 (Oxct2) (Imbedded in the Bmp8a gene) |
| NM_026419 | Elastase 3B, pancreatic (Ela3b) |
| NM_031176 | Tenascin XB (Tnxb) |
| NM_130864 | Acetyl-coenzyme A acyltransferase (peroxisomal 3-oxoacyl-Coenzyme athiolase) (Acaa) |
| NM_010997 | Olfactory receptor 54 (Olfr54) |
| NM_031170 | Keratin complex 2, basic, gene 8 (Krt2-8) |
*Six hundred and seventy-five duplicated mouse gene sequences were aligned to the June 2002 human genome assembly by BLAST (with an initial expected value cutoff of <10-10). The best aligned human genes were subsequently used for reciprocal BLAST alignments (against the mouse genome sequence) to establish a putative orthologous relationship between the mouse and human gene pairs. Using results from our human genome duplication analysis [9,37], we examined regions of the human genome where the human genes are involved in recent segmental duplication. †Italics represents genes that are entirely within a duplication in the mouse genome.