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. 2005 Oct 10;171(1):143–152. doi: 10.1083/jcb.200503014

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Copyright © 2005, The Rockefeller University Press

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Figure 4. — Dissociation of the Dmoesin–TRP complex depends on activation of the phototransduction cascade by light. Coimmunoprecipitation of TRP and Dmoesin from D. melanogaster photoreceptors cells. Protein extracts from heads of WT and norpA ^P24 mutant flies were immunoprecipitated using αTRP as indicated, and analyzed in Western blot with αDmoesin. The norpA mutation prevented dissociation of the Dmoesin–TRP complex by light. (bottom) Western blot of the same head extracts probed with αINAD revealed that equivalent amounts of INAD, which interacts with TRP, are present in all samples (n = 4).