Figure 2.

Titration of serum OVA-specific IgG1. (Inset) OVA-specific, IgG2a and total IgG levels from mice treated with PBS or high dose OVA at birth. Serum levels of antibody were determined in PBS (•) or OVA-treated (○) mice following i.p. injections of OVA (50 μg)/alhydrogel at 4 weeks of age and subsequent aeroallergen challenge 12 days later. Titers in PBS-treated mice were at least 32-fold greater than OVA-treated mice. Horizontal axis represent doubling dilutions of serum (log scale) and vertical axis represent units of Ig. (P < 0.05, n = 8).