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. Author manuscript; available in PMC: 2008 Mar 30.
Published in final edited form as: Neurosci Lett. 2007 Feb 14;415(3):237–241. doi: 10.1016/j.neulet.2007.01.074

Figure 3.

Figure 3

Effect of 30 minutes or 6 hours posttreatment with 1 mg/kg of E2 on ischemic total lesion volume induced by p-MCAO. When administered at 30 minutes after occlusion, E2 (n=6) significant decreases the total infarct volume by 40.0% ± 6.9% vs. OVX group (n=7). When administered at 6 hours after occlusion, protective effect of estradiol was demonstrated in 4 of 12 rats (E2# group), with a 57.0 ± 9.0% reduction of the total infarct volume vs. OVX group (n=8), while, no protective effect was identified in the other 8 rats (E2 group). *P<0.05 vs. control.