TABLE 3.
Amino acid content in DHFRs from M. profunda, E. coli, and T. maritima
Organism | % Amino acid content in DHFR
|
Σa (%)
|
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D | E | F | G | I | K | L | M | N | P | Q | R | V | LVIMF | KRED | |
M. profunda | 5.6 | 8.0 | 2.5 | 6.2 | 6.7 | 3.1 | 10.5 | 3.1 | 5.6 | 5.9 | 3.7 | 5.6 | 6.7 | 29.6 | 22.3 |
E. coli | 8.8 | 6.9 | 3.8 | 6.3 | 7.5 | 4.4 | 6.9 | 3.1 | 3.0 | 6.3 | 2.5 | 5.7 | 6.9 | 28.2 | 25.8 |
T. maritima | 2.9 | 9.9 | 9.3 | 8.1 | 4.7 | 7.6 | 8.7 | 1.7 | 3.5 | 5.2 | 0.0 | 7.6 | 11.6 | 36.0 | 28.0 |
Sum of percentages for the cognate residues.