FIG. 2.

Pathways of siderophore and menaquinone synthesis in Y. enterocolitica, E. coli, P. fluorescens, and P. aeruginosa. MenF (E. coli), EntC (E. coli), PmsC (P. fluorescens) and PchA (P. aeruginosa) are ICSs which convert chorismate into salicylate. In E. coli, isochorismate is converted into o-succinylbenzoate by MenD and MenC and into 2,3-dihydroxybenzoate by EntA and EntB. Pseudomonas converts isochorismate into salicylate by PmsB/PchB. Irp9 shows similarities to ICSs but shows a higher degree of similarity to anthranilate synthase (see Fig. 1b).