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CD4+ T cell response to ESO157–170 vaccine. (A) There is a significant relationship between the number of vaccines and the maximal number of detectable ESO157–170-reactive CD4+ T cells (P = 0.002) when data from all patients are examined cumulatively. (B) CD4+ T cells were stimulated with ESO157–170 peptide and tested against target cells (T-APC loaded with ESO157–170 peptide or irrelevant peptide Flu NP206–229, Flu NP) by IFN-γ ICS.
