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Long-lived T cell immunity. (A) ESO157–170-specific CD4+ T cell response at 6 months for patient 2. (B) A2/ESO157–165 multimer-reactive CD8+ T cells recognized SK-Mel-37 and MZ-Mel-19, but not SK-Mel-23, when tested for CD107a/b and IFN-γ by ICS.