Table 3.

Frequency of deletions/insertions in human V region genes

Population	Mutated V genes	V genes with deletion/insertion		Reference
		Pot. functional	Nonfunctional
HD and NHL	yes	7/72 (10%)	6/11 (54%)	6-12
Plasma cells	yes	5/32 (16%)	2/4  (50%)	†
GC B cells	yes	3/70 (4%)	12/28 (43%)	‡
IgD B cells	no	0/62	0/13	‡
Unmutated Vκ from mutated NHL and HD	no		0/14	6-8, 11

HD, Hodgkin’s disease, NHL, non-Hodgkin’s lymphoma; pot., potentially. 

^†M. Fischer, and R.K., unpublished work. 

^‡Present work.