Population analysis with nafcillin for four naive host methicillin-susceptible S. aureus transformants. Symbols: •, wild-type naive host with cloning vector pAW8 only; ▵, naive host transformed with pYK20, carrying unregulated mecA; ×, naive host transformed with pYK644, carrying the intact mecI-mecR1-mecA complex; ▴, naive host cotransformed with pYK20 and pZRI, carrying the intact blaI-blaR1-blaZ complex.