FIG. 3.
Detection by Western blot analysis of PBP2a (78 kDa) encoded by mecA. COLn(pAW8) is the positive control; COLnex(pAW8), RN4220(pAW8), and RN4220(pZRI)(pAW8) are the negative controls. (a) Comparison of experienced host and naive host transformants carrying pYK20. (b) Representative transformants with cloning vector pAW8 only, pYK644 (carrying intact mecR1-mecI-mecA), and pYK20 (carrying unregulated mecA) and cotransformants with pZRI (carrying blaR1-blaI-blaZ). All were grown under noninducing conditions.