TABLE 3.
Characteristics of the vaginal lavage samples from HIV-1-infected women
| Groupa | Patient IDb | Vaginal viral load (no. of copies/lavage) | No. of MAGI plaquesc | Cocultured | pH | GTIe |
|---|---|---|---|---|---|---|
| Low viral load | 16 | <1,000 | 3 | ND | 5.0 | |
| 21 | <1,000 | 2 | ND | 4.7 | ||
| 34a | <1,000 | 1 | ND | 5.8 | Yeast | |
| 40a | <1,000 | 4 | ND | 4.0 | Yeast | |
| 49 | <1,000 | 3 | ND | 4.0 | Yeast | |
| 77 | <1,000 | 1 | ND | 4.7 | ||
| 91 | <1,000 | 3 | ND | 4.0 | ||
| 1000 | <1,000 | 3 | ND | 4.0 | ||
| 1015a | <1,000 | 0 | ND | 5.0 | ||
| 1024 | <1,000 | 4 | ND | 5.0 | ||
| 56 | 1,800 | 5 | − | 5.0 | ||
| 40b | 2,000 | 4 | − | 4.0 | Yeast | |
| 42 | 4,300 | 0 | − | 5.0 | ||
| 34b | 4,800 | 16 | − | 6.0 | Yeast, BV | |
| 41 | 5,400 | 0 | − | 5.0 | HSV | |
| 74 | 5,400 | 6 | − | 6.0 | ||
| 1 | 9,100 | 7 | − | 5.0 | Yeast | |
| Medium viral load | 22 | 11,000 | 11 | − | 6.0 | |
| 64 | 15,000 | 5 | − | 5.0 | BV | |
| 50 | 16,000 | 21 | − | 6.0 | Yeast, BV | |
| 36 | 22,000 | 9 | − | 5.0 | ||
| 26 | 23,000 | 3 | − | 5.0 | Tric, BV | |
| 28 | 24,000 | 10 | − | 5.0 | ||
| 78 | 36,000 | 11 | − | 5.0 | Yeast | |
| 11a | 44,000 | 7 | − | 5.0 | Yeast | |
| 1021 | 47,000 | 3 | ND* | 4.1 | ||
| 1007 | 50,000 | 1 | − | 6.0 | Tric | |
| 1023 | 53,000 | 1 | − | 3.6 | Yeast | |
| 20 | 56,000 | 9 | ND* | 5.0 | Yeast, BV | |
| 13 | 57,000 | 18 | − | 6.0 | Tric | |
| 84 | 64,000 | 4 | − | 5.8 | Yeast, Tric | |
| 1008 | 71,000 | 0 | ND* | 5.0 | ||
| 14 | 88,000 | 27 | ++ | 7.0 | Yeast | |
| High viral load | 61 | 100,000 | 36 | − | 4.0 | Yeast |
| 7 | 110,000 | 9 | − | 4.0 | ||
| 11b | 110,000 | 16 | − | 4.8 | ||
| 1033 | 160,000 | 0 | − | 4.7 | ||
| 1034 | 260,000 | 19 | − | 5.6 | ||
| 71 | 260,000 | 0 | − | 5.0 | Yeast | |
| 55 | 270,000 | 54 | +++ | 5.0 | ||
| 75 | 270,000 | 2 | ND* | 4.0 | Yeast | |
| 1015b | 280,000 | 3 | ++ | 3.6 | ||
| 45 | 410,000 | 8 | ++ | 4.0 | ||
| 67 | 410,000 | 17 | +++ | 5.0 | Yeast | |
| 1013 | 430,000 | 0 | − | 4.7 | ||
| 63 | 430,000 | 9 | ++ | 6.0 | HSV | |
| 18 | 690,000 | 5 | − | 4.0 | ||
| 1030 | 4,300,000 | 6 | − | 5.0 | ||
| 3 | 12,000,000 | 18 | − | 5.0 | Yeast |
Groups were based on vaginal viral load level: low (<104 total copies, n = 17), medium (>104 to <105 total copies, n = 16), and high (>105 total copies, n = 16).
ID, identification number. Patients 11, 34, 40 and 1015 each had two lavage samples that were collected on different dates.
Number MAGI plaques above the background level. The data are expressed as the average of duplicate wells. Plaque numbers significantly above background (≥5) are indicated in boldface.
p24 detection in cultures at day 21 (in picograms/milliliter): −, <15; +, ≥15 to <100; ++, ≥100 to <1,000; and +++, ≥1,000. ND, not done; ND*, not done because of contamination.
Type of GTI documented on the day of sample acquisition, including infection with T. vaginalis (Tric), infection with HSV (HSV), bacterial vaginosis (BV), and yeast infection (yeast).