TABLE 3.
Mutations identified in 69 INH-resistant isolates of M. tuberculosis from Brazil
| No. of isolates (origin) | No. of mutated isolates, specific mutation(s)
|
|||
|---|---|---|---|---|
| katG | inhA | ahpC | katG/ahpC | |
| 31 (RS) | 25, S315T; 2, S315N | —a | 1, G(−6) A; 1, G(−9) A; 1, C(−30)T; 1, C(−39)T | 1, S315T/G(−6)A |
| 23 (RJ) | 13, S315T; 1, S315I | 1, S94A | 1, G(−6) A; 1, C(−15)T; 1, C(−30)T; 1, T(−40)C; 1, F10I | 1, S315T/G(−6)A; 1, S315I/T(−40)C; 1, S315T/F10I |
| 15 (SP) | 7, S315T; 2, S315N | — | 1, C(−39)T | — |
—, no mutation.