TABLE 1.
Penicillin treatment success and failure
| Variable | Penicillin treatment/outcomeb
|
P value | |
|---|---|---|---|
| Failure (n = 32 [32%]) | Success (n = 67 [68%]) | ||
| Age (yr) | |||
| ≥2, <5 | 8 (25) | 13 (19) | |
| ≥5, <9 | 20 (62) | 38 (57) | |
| ≥9, <16 | 4 (13) | 16 (24) | 0.22c |
| Gender, male | 21 (66) | 35 (52) | 0.21 |
| 1st visit symptoms | |||
| Sore throat | 31 (97) | 65 (97) | 0.97 |
| Sore glands | 23 (72) | 48 (72) | 0.98 |
| Fever | 21 (66) | 55 (82) | 0.07 |
| Inflamed pharynx | 29 (91) | 63 (94) | 0.54 |
| Pharyngeal exudates | 14 (44) | 29 (43) | 0.97 |
| Enlarged glands | 25 (78) | 45 (67) | 0.26 |
| Biofilm formation | 32 (100) | 67 (100) | 1.00 |
| Biofilm log CFU | |||
| Mean | 3.3 (SD = 1.0) | 3.2 (SD = 1.0) | 0.55 |
| Low (≤ 103) | 13 (41) | 30 (45) | |
| Medium (> 103, ≤ 104) | 13 (41) | 26 (39) | |
| High (> 104) | 6 (18) | 11 (16) | 0.68d |
a
By age, gender, symptoms at the first physician visit, biofilm formation, and efficiency of biofilm formation among children 2 to 18 years of age in Calgary, Alberta, Canada, from November 1994 to March 1996.
b
Number (percent). SD, standard deviation.
c
P value for the relationship between age and penicillin treatment outcome.
d
P value for the relationship between efficiency of biofilm formation and penicillin treatment outcome.