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. 2003 Sep;41(9):4043–4048. doi: 10.1128/JCM.41.9.4043-4048.2003

TABLE 2.

GAS isolates for which MICs indicate resistance and MBECs indicate insensitivity by biofilm-forming efficiency

Antibiotic (dose) No. of isolates (%)
P value for insensitivity in relation to increasing efficiency
MIC
MBEC
L M H Total (n = 50) L M H Total (n = 30)
Penicillin (5 μg/ml) 0 0 0 0 (0.0) 6 5 7 18 (60) 0.65
Penicillin + rifampin (7 μg/ml) 0 0 1 1 (0.3) 9 9 10 28 (93) 0.38
Rifampin (7 μg/ml) 1 1 5 7 (23) 7 9 10 26 (87) 0.05
Erythromycin (2 μg/ml) 0 0 0 0 (0.0) 9 9 10 28 (93) 0.38
Clindamycin (10 μg/ml) 0 0 0 0 (0.0) 8 9 10 27 (90) 0.14
Cephalexin (18 μg/ml) 0 0 0 0 (0.0) 9 8 9 26 (87) 1.00
Ceftriaxone (270 μg/ml) 0 0 0 0 (0.0) 8 8 6 22 (73.3) 0.32
a

L, low-efficiency biofilm formation (≤103); M, medium-efficiency biofilm formation (>103, ≤104); H, high-efficiency biofilm formation (>104).