TABLE 2.
MSCRAMM gene distribution among 157 S. aureus clinical isolates
Gene | No. (%) of isolates
|
Odds ratio (95% CI), P valuea | ||
---|---|---|---|---|
Nasal colonization (n = 82) | Native-valve endocarditis (n = 88) | Hematogenous osteomyelitis and/or arthritis (n = 37) | ||
bbp | 17 (21) | 4 (11) | 14 (38) | 5.2 (1.5-17.7), 0.006 |
cna | 30 (37) | 12 (32) | 15 (41) | 1.5 (0.6-3.8), 0.43 |
eno | 82 (100) | 38 (100) | 37 (100) | NS |
ebpS | 45 (55) | 23 (61) | 23 (62) | 1.1 (0.4-2.7), 0.88 |
fnbA | 26 (32) | 11 (29) | 7 (19) | 0.6 (0.2-1.7), 0.31 |
fnbB | 34 (42) | 21 (55) | 12 (32) | 0.4 (0.152-0.99), 0.046 |
fib | 67 (82) | 29 (76) | 29 (78) | 1.1 (0.4-3.3), 0.83 |
clfA | 82 (100) | 38 (100) | 35 (95) | 2.1 (1.6-2.6), 0.146 |
clfB | 82 (100) | 38 (100) | 37 (100) | NS |
Odds ratios and the chi square test were used to simultaneously analyze the distribution of nine MSCRAMM genes among S. aureus isolates from patients with osteomyelitis and/or arthritis versus native-valve endocarditis. CI, confidence interval. NS, no significant difference.