Table 1.
Mice | TCRmedCD4hiCD8med
|
TCRmedCD4medCD8hi
|
TCRmedDPhi
|
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
K+7R+ | K+7R− | K−7R+ | K−7R− | Total | K+7R+ | K+7R− | K−7R+ | K−7R− | Total | K+7R+ | K+7R− | K−7R+ | K−7R− | Total | |
N | 0.06 | 0.02 | 0.32 | 0.46 | 0.86 | 0.04 | n.d. | 0.11 | 0.42 | 0.45 | n.d. | n.d. | 0.18 | 3.69 | 3.89 |
IKO | 0.05 | 0.02 | 0.23 | 0.42 | 0.72 | n.d. | n.d. | n.d. | 0.44 | 0.44 | n.d. | n.d. | 0.16 | 5.22 | 5.38 |
IIKO | n.d. | n.d. | 0.18 | 0.69 | 0.87 | 0.04 | 0.01 | 0.16 | 0.24 | 0.45 | n.d. | n.d. | 0.20 | 14.7 | 14.90 |
DKO | n.d. | n.d. | n.d. | 0.35 | 0.35 | n.d. | n.d. | n.d. | 0.24 | 0.24 | n.d. | n.d. | n.d. | 38.4 | 38.40 |
N: normal; IKO: MHC-IKO; IIKO; MHC-IIKO; DKO: MHC-I and IIKO; K: c-Kit; 7R: IL-7R.
Data are shown as percent of total thymocytes (mean value of three thymuses in each group); n.d.: not detectable (<0.01%).