TABLE 1.
Specificity of the NS5-based MIA tested against various human sera
| Specimen type | No. of sera | Mean MFI (range) | SD | No. positivea |
|---|---|---|---|---|
| Syphilis (T. pallidum positive) | 10 | 1,862 (7-3,375) | 1,241 | 0 |
| B. burgdorferi infection | 10 | 2,312 (1,567-2,768) | 563 | 0 |
| HIV infection | 10 | 2,009 (299-7,517) | 2,127 | 1 |
| A. phagocytophilum infection | 10 | 2,030 (1,046-3,427) | 825 | 0 |
| Antinuclear antibody positive | 10 | 1,680 (477-3,723) | 1,680 | 0 |
| Rheumatoid factor positive | 6 | 730 (85-1,377) | 730 | 0 |
| Herpes simplex virus positive | 5 | 1,902 (1,031-2,797) | 1,902 | 0 |
| Cytomegalovirus infection | 5 | 1,613 (7-3,480) | 1,492 | 0 |
| Epstein-Barr virus infection | 5 | 2,002 (1,111-2,727) | 631 | 0 |
| JE virus vaccine recipients | 10 | 1,633 (638-3,316) | 984 | 0 |
| YF virus vaccine recipients | 19 | 2,563 (966-5,056) | 1,179 | 1 |
| Normal | 20 | 1,811 (970-3,878) | 853 | 0 |
| Total | 120 | 2 |
a
The cutoff for positivity for NS5 is 4,366.