Table 2.
Erythroid parameters
Mice | n | RBC, 106/mm3 | Hb, g/dl | Hct, % | MCV, fl |
---|---|---|---|---|---|
HFE+/+ | 11 | 10.1 ± 0.5 | 16.7 ± 0.5 | 48.6 ± 2.1 | 48.8 ± 1.3 |
HFE+/+ + iron | 6 | 9.9 ± 0.5 | 16.5 ± 0.4 | 48.2 ± 1.6 | 49.3 ± 1.5 |
HFE−/− | 11 | 10.1 ± 0.4 | 16.7 ± 0.7 | 49.9 ± 1.7 | 49.2 ± 0.8 |
HFE−/− + iron | 6 | 10.0 ± 0.6 | 17.0 ± 0.6 | 51.9 ± 2.4 | 51.8 ± 0.9 |
Red blood cells (RBC), hemoglobin concentration (Hb), hematocrit (Hct), and mean corpuscular volume (MCV) analyzed in male and female wild-type (HFE+/+) and mutant (HFE−/−) littermates at 10 weeks of age. HFE+/+ + iron and HFE−/− + iron are mice fed with an iron-supplemented diet containing 2% (w/w) carbonyl iron for 14 days before sacrifice. n, number of animals. Data are presented as mean ± SD.