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Domain organization of the FATP family of proteins. (A) Amino acid sequence alignments of the ATP-AMP motif (common to all members of the adenylate-forming superfamily of enzymes) and the FATP-VLACS motif (restricted to the FATP family) from Fat1p and the six murine FATP orthologues. (B) Cartoon showing the approximate positions of the two elements of the ATP-AMP (white rectangles) and the FATP-VLACS (black rectangle) motifs in the FATP family of proteins. aa, amino acids.
