TABLE 3.
Plasma cytokine values in 38 patients with SCAP correlated to when the sample was obtained after admission to the hospital
| Cytokine | Median (interquartile rangea) pg/ml atb:
|
|||||
|---|---|---|---|---|---|---|
| Admission (n = 15) | Day
|
|||||
| 1 (n = 28) | 2 (n = 30) | 3 (n = 30) | 5 (n = 27) | 7 (n = 11) | ||
| TNF-α | 14.2 (11.9-28.06) | 12 (7.8-20.5) | 10.5 (7.4-20.2) | 14.4 (9.4-19.5) | 17 (8.5-32.2) | 20.4 (12.8-33.1) |
| IL-6 | 423 (162.1-1292) | 218 (100.3-218.3) | 83.8† (32-245) | 66.41† (33.8-171.6) | 29.51† (17.3-110.3) | 71† (29-155.6) |
| IL-8 | 4.8 (2.1-27.1) | 5.37 (1.9-17.9) | 1.74‡ (0.7-4.5) | 2.45‡ (1.03-4.9) | 3.1 (1.9-7.4) | 2.8 (2.5-14.4) |
| IL-10 | 11.85 (6.8-24.9) | 8.8 (4.3-23.9) | 6.4 (3.4-13) | 5.7* (1.8-8) | 5.5* (3.1-9.4) | 9.5‡ (3.5-15.8) |
a
First and third quartiles.
b
Statistically significant decreases over time in relation to basal levels of IL-6, IL-10, and IL-8 were determined with the Kruskal-Wallis nonparametric test and are indicated as follows: *, P < 0.01; †, P < 0.001; ‡, P < 0.05.