TABLE 2.
Suggested ranges for categorization of PC-ELISA results and sensitivity for detection of prior E. ruminantium infection
| PI | Interpretation
|
Sensitivity for detection of previous E. ruminantium infectiona (%)
|
||
|---|---|---|---|---|
| Goats | Cattle | Goats | Cattle | |
| <50 | Not previously exposed to E. ruminantium | Probably not previously exposed to E. ruminantium | NA | NA |
| 50-70 | Cross-reaction with other Ehrlichia sp. or weakly positive for E. ruminantiumb | Weakly positive for E. ruminantiumb or cross-reaction with other Ehrlichia sp. | 100 | 86 |
| 71-85 | Prior infection with or exposure to E. ruminantiumb or Ehrlichia sp. | Prior infection with or exposure to E. ruminantium | 100 | 79 |
| >85 | Prior infection with or exposure to E. ruminantium | Prior infection with or exposure to E. ruminantium | 91 | 31 |
a
Where the cutoff is the lowest value in the range given and sensitivity for detection of previous E. ruminantium infection is calculated from results with experimental infections. NA, not applicable.
b
Except in situations where suitable Amblyomma vectors are considered to be absent.