FIG. 1.

ADCC activities against EBV-infected Raji cells provided by i.v. IgG preparations. The ADCC potentials of i.v. IgG and plasma samples against EBV-positive Raji cells and EBV-negative Ramos cells were tested. The mean ± SD percentage of specific cell death following incubation of the targets with blood lymphocytes is shown. The IgG concentrations in the i.v. IgG preparations and plasma samples are indicated. A plasma pool was prepared with plasma from 12 donors and had 8.611 g of IgG per liter. PBS and 5% sorbitol replaced i.v. IgGs in the samples. All experimental points were run in triplicate. The results of one representative experiment from a total of four that were conducted are shown. BRP with human IgGs was used as a control and was obtained from European Directorate for the Quality of Medicines.