Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Methylation restricts replication initiation events to sequences within or immediately adjacent to the myc origin. Neutral/neutral 2-D gel electrophoresis of unmethylated or methylated replication intermediates after restriction digestion to generate region A (green), region B (blue), and region C (red). Three typical replication intermediates are depicted: the Y arc, the double Y arc, and the bubble arc (8, 27). Arrowheads indicate the positions of predicted bubble arcs.
