Postnatal growth of Plk2−/− mice. (A) Newborn Plk2−/− mouse (asterisk) is small and pale. (B) Enlarged picture showing the incompletely closed eyelids of a newborn Plk2−/− mouse. (C and D) Plk2−/− and wild-type mice have similar growth curves. Males and females were weighed separately starting from postnatal day 21 (P21) (D). The shaded lines represent wild-type mice, and the solid lines represent Plk2−/− mice. The open and solid squares represent males, and the circles represent females. The error bars indicate standard deviations. (E) Plk2−/− and wild-type mice show similar growth rates. The growth rate was calculated by expressing the weight gain as a percentage of the initial weight for each specified growth period. The shaded symbols represent wild-type animals, and the solid symbols represent Plk2−/− mice. Triangles, male and female; squares, male; circles, female.