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E. coli genes found to be essential and preserved in over 80% of diverse bacterial genomes (ERI > 0.8). These universal essential genes are grouped by functional categories (described in Table 2). NTP, nucleotide triphosphate; FMN, flavin mononucleotide; FAD, flavin adenine dinucleotide; CoA, coenzyme A; TCA, tricarboxylic acid cycle; PRPP, phosphoribosyl pyrophosphate.
