TABLE 2.
Distribution of essential and nonessential genes and average ERIs in selected functional categoriesa
Functional category | Description | Total no. of ORFs | No. E | No. N | No. ? | No. ND | % E | Mean ERI |
---|---|---|---|---|---|---|---|---|
AAM | Amino acid metabolism | 138 | 21 | 108 | 1 | 8 | 15 | 0.5 |
CHM | Carbohydrate metabolism | 219 | 21 | 178 | 3 | 17 | 10 | 0.4 |
NCM | Nucleotide and cofactor metabolism | 181 | 53 | 119 | 2 | 7 | 29 | 0.5 |
LPC | Lipid, lipopolysaccharide, lipoprotein, peptidoglycan, and cell wall biosynthesis | 126 | 34 | 73 | 5 | 14 | 27 | 0.5 |
NAM | Nucleic acid metabolism | 156 | 43 | 96 | 5 | 12 | 28 | 0.6 |
PMS | Protein metabolism and secretion | 167 | 80 | 57 | 18 | 12 | 48 | 0.7 |
MSM | Miscellaneous metabolism | 94 | 14 | 72 | 2 | 6 | 15 | 0.4 |
BEN | Bioenergetics | 100 | 15 | 75 | 4 | 6 | 15 | 0.3 |
SMC | Signaling, motility, and chemotaxis | 153 | 12 | 125 | 3 | 13 | 8 | 0.3 |
RCD | Expression regulation and cell cycle and division | 177 | 30 | 118 | 13 | 16 | 17 | 0.2 |
MTR | Membrane transport | 276 | 22 | 244 | 3 | 7 | 8 | 0.3 |
PHT | Phage- and transposase-related processes | 62 | 12 | 35 | 2 | 13 | 19 | 0.3 |
CAT | All categorized | 1,849 | 357 | 1,300 | 61 | 131 | 19 | 0.4 |
UNC | Uncategorized | 2,442 | 263 | 1,826 | 157 | 196 | 11 | 0.2 |
Total | Categorized and uncategorized | 4,291 | 620 | 3,126 | 218 | 327 | 14 | 0.3 |
Abbreviations are as follows: E, essential; N, nonessential; ND, not determined; ?, ambiguous.