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. Author manuscript; available in PMC: 2007 Aug 3.
Published in final edited form as: Dev Biol. 2007 Mar 3;305(2):564–576. doi: 10.1016/j.ydbio.2007.02.037

Table 2.

Quantification of CC10 and SP-C marker expression.

CC10 SP-C
Wild-type and E2f4 +/− 64.4 +/− 10.1 7.7+/− 2.3
E2f4 −/− 34.1 +/− 17.1 8 +/− 2.8
n (pairs) 8 4
p value 0.00013 0.31

For each stain pairs of matched sections from an 18.5 dpc E2f4−/− embryo and a wild-type or E2f4+/− littermate were analyzed. A minimum of 200 bronchiolar (CC10) or 350 lung (SP-C) nuclei were counted per section and each cell scored for strong staining with CC10 or staining with SP-C antibodies. The number of pairs of independent embryos analyzed is indicated (n). The mean % of positive cells +/− standard deviation is presented and the data analyzed using a paired Student’s t-test and the p values indicated.