Table 1.
Genes Coexpressed with E2-EPF in Cancer Microarray Studies.
| Gene | # | Description | Cell Cycle* |
| CCNB2 | 9 | cyclin B2 | G2/M |
| TOP2A | 9 | topoisomerase (DNA) II alpha 170kDa | G2 |
| CENPA | 8 | centromere protein A | G2 |
| CDC20 | 7 | cell division cycle 20 homolog (S. cerevisiae) | G2/M |
| MYBL2 | 7 | v-myb myeloblastosis viral oncogene homolog (avian)-like 2 | ND |
| PRC1 | 7 | protein regulator of cytokinesis 1 | M/G1 |
| STK6 | 7 | aurora kinase A | G2 |
| TPX2 | 7 | TPX2, microtubule-associated, homolog (Xenopus laevis) | ND |
| UBE2C | 7 | ubiquitin-conjugating enzyme E2C | G2 |
| BUB1 | 6 | BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) | G2/M |
| CDC2 | 6 | cell division cycle 2, G1 to S and G2 to M | G2 |
| CKS2 | 6 | CDC28 protein kinase regulatory subunit 2 | G2/M |
| DLG7 | 6 | discs, large homolog 7 (Drosophila) | ND |
| FOXM1 | 6 | forkhead box M1 | G2 |
| MAD2L1 | 6 | MAD2 mitotic arrest deficient-like 1 (yeast) | ND |
| MELK | 6 | maternal embryonic leucine zipper kinase | G2/M |
| RRM2 | 6 | ribonucleotide reductase M2 polypeptide | S |
| TACC3 | 6 | transforming, acidic coiled-coil containing protein 3 | G2/M |
| TTK | 6 | TTK protein kinase | G2/M |
| BIRC5 | 5 | baculoviral IAP repeat-containing 5 (survivin) | G2/M |
| C10orf3 | 5 | centrosomal protein 55kDa (CEP55) | ND |
| CCNB1 | 5 | cyclin B1 | G2/M |
| CDCA3 | 5 | cell division cycle associated 3 | ND |
| CDCA8 | 5 | cell division cycle associated 8 | ND |
| H2AFX | 5 | H2A histone family, member X | S |
| MKI67 | 5 | antigen identified by monoclonal antibody Ki-67 | G2 |
| NUSAP1 | 5 | nucleolar and spindle associated protein 1 | ND |
| PTTG1 | 5 | pituitary tumor-transforming 1 | M/G1 |
| ZWINT | 5 | ZW10 interactor | ND |
| AURKB | 4 | aurora kinase B | G2 |
| BUB1B | 4 | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | G2/M |
| CCNA2 | 4 | cyclin A2 | G2 |
| DKFZp762E1312 | 4 | hypothetical protein DKFZp762E1312 | G2 |
| EZH2 | 4 | enhancer of zeste homolog 2 (Drosophila) | S |
| HCAP-G | 4 | non-SMC condensin I complex, subunit G | ND |
| KIAA0101 | 4 | p15(PAF) | ND |
| KIF11 | 4 | kinesin family member 11 | ND |
| KIF20A | 4 | kinesin family member 20A | ND |
| KIF4A | 4 | kinesin family member 4A | ND |
| KNTC2 | 4 | kinetochore associated 2 | ND |
| KPNA2 | 4 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | G2 |
| NEK2 | 4 | NIMA (never in mitosis gene a)-related kinase 2 | G2/M |
| RAMP | 4 | RA-regulated nuclear matrix-associated protein | ND |
| TRIP13 | 4 | thyroid hormone receptor interactor 13 | ND |
| CDCA1 | 3 | cell division cycle associated 1 | G2/M |
| CDKN3 | 3 | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | M/G1 |
| CENPE | 3 | centromere protein E, 312kDa | G2/M |
| CENPF | 3 | centromere protein F, 350/400ka (mitosin) | G2/M |
| FLJ10719 | 3 | hypothetical protein FLJ10719 | ND |
| HMMR | 3 | hyaluronan-mediated motility receptor (RHAMM) | G2/M |
| KIF23 | 3 | kinesin family member 23 | ND |
| KIF2C | 3 | kinesin family member 2C | ND |
| KIFC1 | 3 | kinesin family member C1 | G2 |
| LOC146909 | 3 | hypothetical protein LOC146909 | ND |
| MCM10 | 3 | MCM10 minichromosome maintenance deficient 10 (S. cerevisiae) | ND |
| PBK | 3 | PDZ binding kinase | ND |
| RACGAP1 | 3 | Rac GTPase activating protein 1 | ND |
| TYMS | 3 | thymidylate synthetase | S |
The gene name and cellular processes associated with ECGs, as well as their frequency of occurrence in the 20 analyzed cancer microarray studies.
#, frequency with which the indicated gene was identified as correlated with E2-EPF in the 20 microarray studies.
*
Cell cycle phase determined in Whitfield et al [6]; ND, not cell-cycle regulated or not designated.